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Sex and regional differences in estrogenic effects on ER- and PR-m RNA abundance were found.
Females responded to EB treatment with increases in ER-and PR-m RNA relative abundance in the ventromedial nucleus of the hypo-thalamus (VMH).
ER-m RNA decreases in the lateral septum and PR-m RNA increases in the posterior hypothalamus with hormone treatment were also found, but did not differ by sex.
Neither sex nor treatment effects were definitively shown for ER- or PR-m RNA abundance in the anterior hypothalamus-preoptic area.